A prostate cancer research study focused on 'hormone therapy' is looking for an additional 20 participants for an opinion research project. Ideally participants will be on Lupron -or- have used Lupron -or- 'another form of hormone therapy', within a reasonably recent time frame. Participants need to have been diagnosed with prostate cancer sometime during the past 6 years.
Participants, and possibly members of their family, will spend approximately one hour with an interviewer over the phone. For this, participants will be compensated an honorarium of $150.
If interested to find out more information, and to see if you qualify for this study call:
David Leonard, Director of Opinion Research in New York, NY at 1-212-289-0087.
Be sure to tell him you heard about the study from Steve Warren at Release Prostate Cancer Now.
Monday, February 1, 2016
Wednesday, January 20, 2016
Want a Better Life, Avoid Cancer, Heal Faster... Exercise
Want to live longer and fell
better while avoiding a cancer or its recurrence?
The solution is as simple as exercising 3-4 hours per week. You’ll reduce your risk of getting cancer by over 60%, and reduce your risk of a cancer relapse by 40%. Incredible benefits for only a few hours per week, yet how many just can’t find the time to exercise, or even move their body beyond work, home, and refrigerator.
The solution is as simple as exercising 3-4 hours per week. You’ll reduce your risk of getting cancer by over 60%, and reduce your risk of a cancer relapse by 40%. Incredible benefits for only a few hours per week, yet how many just can’t find the time to exercise, or even move their body beyond work, home, and refrigerator.
It doesn’t take much. A 2011 study
looking at men diagnosed with prostate cancer found just 3 hours of vigorous
physical activity per week lowered their risk of dying from cancer by 61%. Men
over 65 with prostate cancer who exercise regularly enjoy even better odds.
Just 3 hours exercise per week reduced their risk of dying by a whopping 70%.
Expanding the benefits of exercise, the Macmillan Cancer Support Study, a review 60 studies and survey of 400 health care
professionals, found that breast cancer patients reduced their mortality by 40%
with exercise, and bowel cancer patients reduced their risk of dying by 50%.
And if you were exercising before
your cancer diagnosis, your odds are even better. Now think about this, many men and women don’t even
realize they have cancer till its been growing inside for a long time. This is
precious time when you could have been exercising to improve your odds.
Exercise acts on cancer in
multiple ways. It reduces internal inflammation preventing cancer’s occurrence.
In addition, a 2003 study found that exercise increases the p53 tumor suppressor gene while reducing IGF-1. This
acts to stop radical cell growth and promote natural cancer cell death thereby
preventing and stopping cancer in its tracks. In truth, the more active you are
the less possibility of cancer you’ll have. Add to this, the findings out of a
study looking at 572 cancer patients who had their prostates removed because of
cancer. They found men participating in more exercise had more normally shaped
blood vessels in their tumors. Why is this important? Tests have shown more
regularly shaped blood vessels equate to quicker and more complete healing
results after treatment.
Then it’s important to consider
the quality of life after cancer treatment. A 2015 study of women treated for
breast cancer found those who participated in a trainer supervised, slowly
progressive weight training program achieved much better physical functioning
than those who merely rested after treatment. Simple daily activities such as walking, carrying things, even getting out of the bed or shower were all improved for those who exercised over those who did not. Studies also found that breast cancer patients who exercised experienced less nausea, reduced risk of blood clots, had easier digestion with less constipation, reduced weight, enjoyed a healthier sex drive, and experienced more energy.
Activities such as guided
exercise, biking, tennis, jogging, swimming and even fast walking all
contributed to lowering health risks, though some feel they’re only a little
overweight so why put out the effort. Bet you didn’t know you don’t have to be
obese or really fat to increase your risks of cancer. Just 10 to 20 pounds
overweight may start the process. Excess fat actually acts like an organ in
your body. It makes hormones and proteins that increase inflammation that
directly cause cancer. Fat is not just fat. There are over 20 hormones and 80
different harmful proteins made by the fat around your middle. The greater the fat,
the more nasty chemicals are being made. This eventually causes cellular DNA
damage while supporting cancer development, growth, and recurrence. Yet how
many patients have their cancer treated without addressing the overweight
lifestyle that contributed to or created the cancer.
But cancer isn’t the only
consequence. It is well documented that excess fat, especially around your
middle, causes general inflammation throughout your body. This inflammation can
lead to heart attacks, stroke, Alzheimer’s, nervous system disorders and much
more. To live a high quality of life we need to break out of this destructive
process.
So our tasks become staying
physically fit, getting your blood really flowing, and reducing your gut. Have
you taken a good look at the American population recently? How many do you see
walking around with a basketball or worse pushing out from where their stomach
used to be? No man or woman was born like this. Nor did it just happen. It took
years of neglect and abuse to grow that gut, the same gut that may reduce you
to your knees with cancer. Do you now see its time to start making healthier
lifestyle changes?
Yet where do you begin? If you
haven’t been to a gym in awhile, it can be an intimidating process. Then too,
cancer treatment will sap your strength and resolve. Chemotherapy drugs,
radiation, or surgery often cause overwhelming fatigue, muscle pain, diarrhea
or constipation, weakness and more, all things that reduce your resolve to get
the needed exercise that will reduce or relieve these symptoms. Your mind may
say, ‘I need the exercise’, but your body is saying, ‘I can’t do it’, ‘I’m
afraid’, ‘It won’t make a difference’, or ‘I’m just too sore or tired’.
At this point you need to realize,
its your life we are talking about, and if you want to improve your life, its
time to start moving. If you can only do one thing, just get out and walk. Take
30 minutes or an hour a day, and walk around your neighborhood. Meandering with
your dog isn’t nearly as good as a really quick walk. Then start by getting to
the gym at least once a week. Now here’s the important part. If you haven’t
been to the gym before, or if your body has been depleted with cancer
treatments, you will need a personal trainer skilled in working with cancer
patients.
Look for a gym that can provide you
with individualized training and the personalized support specialized in
working with cancer and overweight patients. This will help you renew your
energy while rebuilding your body. Regardless of your current abilities or
challenges, there is no need to worry what others will think of your current
skills or progress. Often a boutique exercise facility, featuring
individualized training and small classes with professionals who understand
your cancer journey, will be best.
If you still need one more reason
to exercise, then hear this! A new 2016 study found fat cells in adipose tissue surrounding the prostate in overweight
men make a chemokine called CCL7. This links with a prostate cancer chemical
labeled CCR3, causing the cancer to spread while becoming much more aggressive,
and creating a much greater chance of recurrence after treatment. Simply put,
fat acts to draw out the cancer from prostates and spread it around the body. From
this study they learned the more overweight you are, the bigger your gut, the
greater chance you will have difficult to treat, aggressive prostate cancer.
The solution is simple, If you
like living, start eating right and exercise today!
Monday, January 11, 2016
Potential New Cancer Treatments: A New Look At Green Tea
Are you a tea drinker? After reading this, you may consume
more green tea. Each cup of tea is loaded with catechins. These are polyphenols
that have been shown to assist with the prevention and treatment of various
cancers. Major polyphenols in green tea include epicatechin (EC),
epicatechin-3-gallate (ECG), epigallocatechin (EGC), and
epigallocatechin-3-gallate (EGCG).
Green tea also contains to a lesser amount the polyphenols kaempferol,
myricitrin and quercetin. Of all the polyphenols in green tea the most abundant
is EGCG. One cup of green tea will contain 300-400mg mixed polyphenols,
including approximately 100-150mg EGCG.
For 5,000 years, Chinese have been drinking green tea. They
also enjoy some of the lowest incidence of prostate cancer. The question
becomes, could this partially be do to the green tea? The answer appears to be
yes. Multiple studies have shown
drinking green tea reduces the risk of cancer. When patients treat their cancer
with it, green tea decreases cancer cell viability along with promoting cancer
cell death. Green tea is unique. It has been found to have either antioxidant
or oxidative effects pending on the health of the cell it reaches, along with
anti-inflammatory, anti-carcinogenic, anti-arteriosclerotic and anti-bacterial
properties. One study found drinking 3 cups of green tea per day lowered prostate cancer risk. Another study looking at 49,920
men in Japan found drinking 5 cups of green tea per day significantly reduced the risk of advanced prostate cancer.
But who really wants to drink that much tea? Could it also cause problems, and
don’t forget about the caffeine.
What if there was something from green tea anyone could take
to obtain the same benefits without the volume of tea, or its caffeine? Truth
be known, it does exist. Researchers have long looked at the benefits of EGC
and EGCG in direct relationship to cancer.
In prostate cancer they found that EGC and EGCG are
effective at reducing the enzyme 5-alpha reductase process thereby inhibiting
the conversion of testosterone into DHT effectively blocking it from cancer
cells.
This process is much like the action of the cancer drug bicalutamide and other
antiandrogen cancer drugs, without the severe side effects. Then again many
believe prostate cancer’s growth is fed by DHT, so reduce DHT and slow the
growth. Researchers also found that EGCG retards the angiogenesis process by
preventing new cancer blood vessel nutrient supply lines, essentially starving
the cancer. In addition researchers discovered when EGCG is used with another
component, it effectively blocks ENOX2 proteins causing interference with the cancer
cell’s ability to mature and divide, effectively cutting their growth.
And there’s still more. EGCG coming into contact with cancer
cells results in the production of hydrogen peroxide. When this H(2)O(2) reacts
with the increased iron stored in, and needed by, cancer cells, potent reactive oxygen species (ROS) are created such as hydroxyl radicals,
creating a heightened oxidative state causing apoptotic cell destruction.
Following this train of thought, new research from Penn State confirmed EGCG from green tea damages the mitochondria of
cancer cells reducing the expression of anti-oxidant genes causing further
oxidative stress leading to cancer’s demise. They also proposed that EGCG
interacts with a protein, SIRT3, to facilitate the process. The truly
remarkable part of this interaction between EGCG and SIRT3 is that, it’s
selective in nature. EGCG turns on SIRT3 in healthy cells, and turns off SIRT3
in cancer cells. How incredible, and what a fabulous design! This unique set of
interactions protects healthy cells, keeping them away from cancer, while
causing cancer cells to terminate.
EGCG is certainly a multi-pathway approach to treat cancer exhibiting unique healing interactions with multiple forms of cancer including
breast, prostate, colon, lung, ovarian and many others.
To further show the benefits of EGCG and EGC for prostate
cancer prevention, an Italian study at the University of Parma, Italy gave
flavonoid concentrates to men who tested prone to the risk of prostate cancer.
The men received 200mg of the concentrate 3 times per day for a year. At the
end of the study only one man out of 32 receiving the green tea flavonoid
capsules was diagnosed with prostate cancer, whereas in the control group not
receiving the capsules, 9 out of 30 men were diagnosed with prostate cancer.
When you consider all these benefits, without many of the
egregious side effects of artificial cancer drugs when administered properly,
it certainly makes one think there could be a better way to approach healing
cancer, or at least slow it down. Yet how many men and women in the general
population know the cancer preventative and healing benefits of EGCG from green
tea? Have you ever heard, you should drink green tea, or try EGCG, from your
doctor in relation to cancer? If not officially ‘FDA Approved’ for cancer
prevention and treatment, for many doctors it doesn’t exist. They simply say
(without FDA Approval) there is no proof it works. For our future, and the
health of our society, I believe we need to find a way to further research and
integrate treatments such as this into everyday clinical practice.
In itself, EGCG may not be the cure-all for cancer, though
it most likely will slow it down, and assist healing when used with existing
approved cancer protocols. Considering new research suggests it operates as a
pro-oxidant creating ROS in relation to cancer cells, further research may want
to look at combining it with other natural oxidative treatments such as
Artemisinin or marijuana.
EGCG may also lesson cancer recurrence rates by effectively reducing
the small amounts of cancer cells left after surgery or radiation. Then too,
there is extensive evidence suggesting EGCG plays a substantial role in cancer
prevention. EGCG presents so many good opportunities to attack cancer. Still it
is also important to remember throughout this discussion, everyone’s unique cancer,
diet, composition, history and metabolism are different. Where some have
received excellent results from EGCG, others have experienced no results
directly attributed to its use for reasons yet unknown.
Aside from the already mentioned healing actions of EGCG,
one unique benefit deserves further exploration. Possibly EGCG’s greatest
benefit comes from its ability to tackle newly developing cancer before the
cancer gets a foothold requiring more drastic treatment. And to my belief,
everyone would agree the sooner a cancer is found, the easier it is to treat
with better results. So how do we find cancer at its earliest stages?
To accomplish this task, I believe we should all be looking
at a newly available test capable of detecting 27 different types of cancer,
and there organ of origin, with a single blood draw including: Prostate,
Bladder, Breast, Cervical, Colorectal, Endometrial, Esophageal, Gastric,
Hepatocellular, Kidney, Leukemia, Non-Small cell, Lung Small cell, Lymphoma,
Melanoma, Mesothelioma, Multiple Myeloma, Myeloma, Ovarian, Pancreatic,
Sarcoma, Squamous Cell, Thyroid,
Follicular, Uterine, Papillary, Testicular Germ Cell cancers. It accomplishes
this by using the ENOX2 protein as a marker, and then determining its molecular weight and isoelectric point. The test,
though not infallible, claims a 99.3% reliability for determining cancer(s)
with no false positives, and 96% accuracy in determining the type of, and organ
site, of the cancer. Certainly better results than the
standard PSA test. This ONCOblot test has been called, “the most sensitive
blood test for cancer available today”. Unfortunately it can’t determine the
stage of the cancer, the amount of the cancer load, or any cancer spread. It
just effectively tells you if you have cancer, or not. Yet when considering
whether to have a biopsy, determining if you have the real possibility of
cancer beforehand is very valuable knowledge. Currently, the ONCOblot test is approved
by the FDA as a ‘Laboratory Developed Test’. Unfortunately, it is not covered
by insurance, as it is too new, and little known by many oncologists. It was
first made available to the public January 2013.
Using this test as a follow-up to the standard PSA test that
so often triggers a biopsy, could save the American public and insurance
companies over $2 Billion per year by dramatically reducing the 750,000
unnecessary negative prostate biopsies. But the real benefit may come from the
millions of lives it could save. You see this test can find cancer even before
major symptoms appear. It detects cancer with as few as 2 million cells, unlike
current mammogram scans that need 4.5 trillion cells to register. And it is at
this cancer infancy stage that EGCG is most effective at eradicating cancer.
Imagine if cancers were found early enough for EGCG, say in the form of
CAPSOL-T® a product combining concentrated EGCG with capsicum powder, or
another green tea product, to heal your cancer without surgery, radiation or
chemotherapy. Could it change your life, and the face of medicine today?
In a cancer prevention trail using CAPSOL-T®, 110 men and
women were tested for the presence of ENOX2 using the ONCOblot process. Forty
four (44) test subjects were found to have the presence of various cancers as
exhibited by positive ONCOblot tests. These were then given CAPSOL-T® for
periods from 3 to 17 months and continually retested for ENOX2 markers. Researchers
found that forty one (41) of the cancer subjects retested no longer showed the
presence of ENOX2 in their systems, indicating there very early stage cancer gone.
CAPSOL-T® is a specialized product readily available in the
U.S. combining concentrated decaffeinated green tea powder in a 25:1 ratio with
capsicum powder otherwise known as red pepper or chili pepper. Each 350mg
CAPSOL-T® capsule has the flavonoid benefits of drinking multiple cups of green
tea with only 1.65mg caffeine per capsule. It is believed the synergy of
concentrated green tea with capsicum increases the bioavailability and healing
qualities many times over. Capsicum by itself has been shown to block breast
cancer cell migration and reduce the size of certain tumors
Those who use CAPSOL-T® are strongly recommended to take it
every four (4) hours around the clock to maximize its effectiveness, along with preventing an EGCG resistance buildup. For those
who want to sleep through the night without interruption, there is a
time-release product available. Structured dosing allows the cancer
cells to be continuously exposed, creating the best possible results. According to CAPSOL-T®, there have been no adverse effects, no liver problems, and no lawsuits associated
with CAPSOL-T® use. It has also been stated that CAPSOL-T® is non-toxic at recommended
concentrations due to the many other protective polyphenols in the product. The
manufacturer of CAPSOL-T® confirms it is all-natural and contains only
decaffeinated green tea and capsicum powder, both of which are extremely safe.
With that said, it is important to know side effects from
using ‘too much’ EGCG and/or green tea could exist. If you have cancer and decide to explore EGCG or CAPSOL-T®, I suggest you
only do it under a doctor’s care who is familiar with the product(s) you are
using. Cases of acute liver failure, even death, have been attributed
to taking too much EGCG and/or caffeine.
Minor side effects can include excess intestinal gas, nausea, heartburn,
stomachache, abdominal pain, dizziness, nervousness, headache, and muscle pain.
More serious side effects from concentrated EGCG could include vomiting, kidney problems, and moderate
to severe hepatic necrosis (liver failure). For most, these side effects
disappear when EGCG supplementation is stopped. The higher the dose of EGCG,
the more toxic it is to the liver, and a small percentage of people, for as yet
undetermined reasons, appear to be especially susceptible to liver problems.
Interesting to note, when used properly, EGCG has been suggested to prevent Hepatitis C, thus protecting the liver.
Before beginning clinical use of EGCG, there is a discussion you need to have with
your doctor, along with a complete liver panel, prior to beginning any EGCG treatment. And since side effect symptoms
have occurred anywhere from 10 days to 7 months after treatment, it is appropriate
to continue to have your liver checked on a regular basis.
To be wise, start by thinking of EGCG as a cancer drug,
rather than a super safe supplement. Would you blindly start taking a cancer
drug? In reality, considering the millions, possibly billions of people around
the world using green tea and EGCG every day with relatively few if any serious
side effects, EGCG is probably safer that driving your car to the corner store
for a carton of milk. Then consider the newest FDA approved cancer drugs with
their litany of side effects such as nausea, diarrhea, vomiting, arm swelling,
reduction in blood cells, high blood pressure, decreased hemoglobin, liver
damage, cardiac dysfunction and arterial events, renal failure, thyroid
failure, gastrointestinal perforation etc, and you realize green tea and EGCG
for cancer, when treated with respect under proper supervision, can be
generally considered safe having excellent healing qualities. The majority of
people never experience any side effects. According to the European Journal of Clinical Pharmacology between 1999 and 2008 only 34 cases of liver damage were attributed
to EGCG, with one unfortunate death.
By the same token, between 1999 and 2008 there were 9 deaths attributed to drinking too much water.
Problems can happen. Everything you put into your mouth has an effect on
your body! Be safe and work with your
doctor for appropriate dosage and proper tests.
Certainly there are laboratory studies
and case studies
showing doses of EGCG unsafe. There is also a ‘wealth of materials and studies’
showing the remarkable benefits of EGCG with zero to minimal side effects. It
is unfortunate we do not have more studies using EGCG in human trials. The
limited research I have seen for CAPSOL-T® is very promising, and I have heard
of no side effects regarding this product. It is also interesting that several
attorneys are gathering clients for class action suits regarding EGCG and its unregulated
use in weight reduction formulas. Though an excess of EGCG looks to be the
culprit in this legal action, much is still unknown about EGCG’s interactions
with other ingredients, the amounts of caffeine consumed, and/or pesticides and
substances that may have contaminated the weight reduction product or tea.
There obviously needs to be more research.
From my research, I believe EGCG and EGC from green tea aid
in the process to relieve the burden of cancer. Drinking green tea daily, as a life
choice, appears to provide a strong avenue for cancer prevention. As a
treatment protocol today I would only personally use EGCG as secondary to other
treatments, or as a primary treatment when cancer is found in its earliest
stages. Then I would look at CAPSOL-T®. When used with low-risk early stage non-aggressive prostate cancer, the benefits appear
clear. We also need to make available better use of the ONCOblot test, if not for the
$2 Billion cost reduction, for lives it will save.
Today EGCG is one more of our low cost, orphan cancer
treatments deserving further research and eventual approval by the FDA, especially
when it comes to early cancer treatment and as a supplemental treatment along
side more aggressive protocols. We all deserve further research into EGCG to understand
dosage over time, most effective applications, and greater product refinement.
Imagine relieving a portion of the burden of cancer for pennies a day. With
nearly 12 cancer deaths per minute, we must do
everything possible to cure cancer now. Not just looking at exotic, outrageously
expensive, new drugs. EGCG has earned its place in the list of Proven Natural
Treatments Deserving Research. The time has come for us to take the next step
and explore it further.
There is still more to explore in this series on Potential New
Natural Cancer Treatments. Look for the new post coming soon.
Wednesday, January 6, 2016
Potential New Natural Cancer Treatments: Turkey Tail and Tocotrienols
It’s 2011 researchers in Canberra declare PSP, an extract from Turkey Tail Mushrooms, 100% effective at suppressing prostate cancer stem cells in mice. Many researchers and doctors currently believed cancer stem
cells are responsible for prostate cancer’s initiation and growth. PSP stands
for polysaccharopeptide. Researchers further concluded that dose dependent PSP
was effective at suppressing cancer formation and an agent for preventing
cancer. Additional studies have found with the inclusion of gamma-tocotrienol, a component of Vitamin-E, healing results are
further enhanced. Gamma-tocotrienol appears to work synergistically with PSP by
sensitizing the cancer cells to allow a faster action of PSP. This has led to a
reduction of cancer colonies by as much as 85% over a short time.
Now realize this work was completed on
mice, though certainly it brings the question as to why there is no immediate
follow-up for human U.S. trials especially considering for decades PSP and PSK
have been official government approved healing drugs in Japan and China for
decades.
Researchers have been looking at turkey tail and
gamma-tocotrienol for many years due to their unique properties. The turkey
tail mushroom, also known as Yun Zhi in traditional Chinese herbal medicine,
Trametes Versicolor, Coriolus Versicolor, Polyporus Versicolor, and Kwaratake
in Japanese medicine has been used throughout Asia for hundreds of years in
soups to boost health and treat serious illness. Derivatives from turkey tail
mushrooms have exhibited immune system enhancement, antimicrobial, antiviral
and mutative cell inhibiting qualities. The two most studied components of
turkey tail are PSK and PSP. PSK is a polysaccharide and PSP is a polysaccharide-peptide.
Both PSK and PSP are known to boost immune cell production,
improve traditional cancer treatments, and relieve symptoms from chemotherapy. Sold
commercially as Krestin in Japan, PSK has been used as a government ‘approved
cancer drug’ since 1977. When used along
with surgery, chemotherapy or radiation it has shown significant improvement in
overall results. Not only does PSK have excellent antioxidant and free radical
scavenging properties, it also inhibits cancer’s spread by reducing adhesion, motility
and cancer cell attachment to blood vessels. Reports have further shown the
restoration of depressed immune systems and enhanced activity of natural killer
cells, T-cells, macrophages and peripheral blood lymphocytes. As an example,
in one 1997 study, when PSK was used in conjunction with chemotherapy to treat breast cancer
patients, 5 and 10-year survival rates were 100% for PSK treated patients and
only 76% and 55% respectively for those treated with chemotherapy alone. These are
exciting results, and breast cancer has many similar characteristics to
prostate cancer. PSK supplemental treatment appears to be received well with
only a few patients experiencing gastrointestinal upset or some darkening of
the fingernails.
Research has shown that
ingesting PSK in as much as 9 grams per day in Japan is considered safe.
As a bonus it does not appear to reduce activity of chemotherapy drugs nor cause genetic damage while enhancing the healing process.
PSP, a Chinese developed medicine, was ‘approved as an
official cancer medicine’ by the Chinese government in 1992/1993. PSP is believed to be more effective than PSK due to
the bonding of a peptide during the extraction process. This allows for easier
and more complete absorption by the body. It’s believed PSP passes through the
intestine and bonds to glucose receptors on lymphocyte macrophages, NK cells
and T-cells. This causes these cells to create disease resistant chemicals like
interferon, interleukins, prostaglandin and other mutation resistant factors.
It also has been shown to stabilize white blood cell count and improve the
overall quality of life for cancer patients. Prostate cancer cells thrive on
glucose, so they also tend to suck up the PSP. Research has shown when PSP
enters cancer cells it down regulates prostate cancer stem cells. Since these
are a foundational factor to cancer’s initiation and progression, targeting
these cancer stem cells is of prime importance.
It is also believed that approved conventional therapies do
little to target cancer stem cells, leaving new cancer to grow after initial
treatment. In addition to targeting cancer stem cells, PSP suppressed the
ability of cancer cells to form prostaspheres and inhibited their
tumorgenicity. This puts a halt to the self-renewal and growth process of
cancer.
Both PSK and PSP from turkey tail resemble each other but
are structurally different. PSK comes from a CM-101 strain of turkey tail with
extraction completed using hot water and then a salting out with ammonium
sulfate. PSP originates from a Cov-1 strain of turkey tail using hot water
extraction and then an alcohol precipitation process.
Chemically they are similar, though PSK contains fucose and PSP contains
rhamnose and arabinose.
Now let’s add Gamma or Delta Tocotrienols into the mix. These come from Vitamin-E. There are four
tocopherols and four tocotrienols in Vitamin-E, each divided into four
components labeled Alpha, Beta, Delta and Gamma. Both tocopherol and
tocotrienol molecules are similar shaped but the tocotrienols have smaller
heads, shorter tails and a higher electron density. This makes them incredibly
more effective and faster at bonding with cell membranes. In addition
researchers have found tocotrienols to be 40 to 60 times more effective as
antioxidants than tocopherols. Natural sources for varying amounts of
tocotrienol and tocopherol include rye, amaranth, barley, rice
bran, ancient wheat, palm fruit, annatto, walnuts, hazelnuts, poppy, safflower, maize, and the seeds of flax,
grape, and pumpkin. The three sources most used for supplements are rice bran,
palm fruit and annatto. Rice and palm have approximately 25% and 50% tocotrienols
respectively with a lot of tocopherols. Only annatto provides a high source of
tocotrienols without the tocopherols. Annatto is approximately 90%
delta-tocotrienol and 10% gamma-tocotrienol. So why is this important?
Studies have shown tocopherol found abundantly in most
Vitamin-E products may interfere with the healing activity to tocotrienol. It’s like one component is racing around to treat
your cancer while the other is putting on the brakes. During a University of Wisconsin
study, researchers looking at the ability of combined tocotrienol and
tocopherol to reduce cholesterol found a general 10% to 22% improvement. But
when they put a non-responsive group of subjects on only delta and gamma
tocotrienols after just 4 weeks they witnessed a 35% to 40% drop in their
cholesterol. From their research they determined delta- and
gamma-tocotrienols exhibited the highest health benefits of all the eight forms
of Vitamin-E. Further research has gone on
to support similar findings leading to the suggestion to not take supplements
with tocopherols within six hours of supplementing with high tocotrienols. This
suggestion can be extremely difficult, as most supplement manufacturers love to
combine all tocopherols and tocotrienols in one gel cap. Another source
suggested taking multi-vitamins with mixed component Vitamin-E in the morning,
and high source tocotrienols in the evening with dinner, so they peak in the
blood about the same time cholesterol production peaks.
Then there is the problem with ‘Synthetic’ Alpha Tocopherol
also on the market. Vitamin-E actually received a bad report not too long ago
when a study found synthetic alpha tocopherol may increase prostate cancer, and
the results were generalized to Vitamin-E. The problem was, most medical
professionals didn’t take into account the difference between synthetic and
natural products, and the fact that synthetic alpha tocopherol was used in the
study without gamma tocopherol to compensate. With all this said, the main point
to remember is that natural delta- and gamma-tocotrienols are believed to be
the most effective components of Vitamin-E when used to treat cancer.
As a cancer killer, delta- and gamma-tocotrienols have
showed interesting results. One of their greatest benefits is the ability to
provide a multi-targeted approach. Some believe cancer cells are created
because of the malfunction of numerous genes and signaling pathways. This is
why drugs, designed to only interact with a single gene of pathway like docetaxel,
eventually fail. Though the designer drug may address one small issue, the
cancer is left with multiple workarounds. Tocotrienols on the other hand have been found to be multi-interactive. They target the COX2, EGFR, TNK, HER2,
bct-abl and VEGF pathways along with inhibiting transcription factors, enzymes,
growth factors, receptors, kinases and anti-apoptotic proteins.
One of the more interesting ways that tocotrienols stop cancer is through an
anti-angiogenesis process. Tumor cells need abundant nutrition for all their
growth. Through angiogenesis they create more blood vessels to supply their
food. Tocotrienols are believed to slow, even stop this process, thereby
putting cancer on a starvation diet while preventing further growth.
Then there’s the unique ability gamma-tocotrienol has to
down regulate, essentially kill, cancer stem cells (CSC’s). Studies have shown
a limited number of cancer stem cells exist within many cancer colonies. They
are considered to be the leaders, or the ones in charge. These cells are
tenacious, with excellent survival and tumor initiating characteristics. In
fact they are so tough that radiation and chemotherapy often leave them behind
to development new cancer years after initial treatment. Gamma-tocotrienol has
been found to effectively deal with these cancer stem cells, and when paired
with other forms of chemotherapy act as a chemo-sensitizing agent for further
cancer stem cell destruction.
Bottom line, tocotrienols work on cancer at a multitude of
different levels to induce cancer’s demise. Long-term consumption of
tocotrienols has been linked to reduce risks of prostate, skin, and breast
cancer, with delta- and gamma-tocotrienols having the best results. For a healthy person, a preventative dose of 50mg
to 100mg per day has been suggested. For those with cancer some suggest 300mg
to 400mg per day though there are no confirming studies. When deciding on which
source of tocotrienols to take there are a few important considerations. Most
important, the good effects of tocotrienols are reduced by the more tocopherols
come with it. So learn to read labels for the highest source of tocotrienols
and the lowest amount of tocopherols. If tocopherols are more than 50% of the
ingredients, the product may not be right for you. Second, only purchase
natural sourced products. There were some ‘synthetic’ alpha-tocopherols used in
a clinical trial that severely depleted gamma-tocopherol and caused DNA damage
resulting in cancer from reactive nitrogen. This is started an anti
alpha-tocopherol and Vitamin-E movement. Much of this research has been
questioned.
You may be wondering with the extensive history of positive
results and research studies regarding the use of turkey tail and tocotrienols
to treat disease and cancer, why the U.S. is not all over researching the
benefits of PSP, PSK and gamma-tocotrienol. Could it be the FDA believes humans
in Japan and China, having government approved cancer-healing benefits from PSK
and PSP over 38 and 22 years respectively, are fundamentally different from
humans in the U.S.? More likely, it is because the U.S. is a wealth-reward
driven society and there’s no money in it. PSP, PSK and tocotrienol are not
newly patentable, cheep to produce, so there’s no money for the massive double
blind studies the FDA requires regarding treatment approval. They are widely
used already as natural healing substances, even as doctor delivered medicines
outside the U.S. Then too, the FDA is not in the business of finding cures for
cancer, their job is to regulate, approve or reject U.S. research. And there’s
the issue, finding a natural inexpensive cure for cancer would put so many
people including doctors out of work, and businesses out of existence.
In 2012 the FDA did approve a $5.4 million Trial of Turkey
Tail Mushroom by Bastyr University together with the University of Washington
and others, for advanced prostate cancer in conjunction with chemotherapy. I
understand the product to be tested was a hot water and alcohol extraction of turkey tail from Host Defense.
The Trial was to begin in 2013. Last I heard this
Trial was cancelled due to lack of participants, puzzling considering there are
over 220,800 new U.S. cases of prostate cancer each year, and over 27,500
Americans who annually die of this terrible disease. Or could it be a reflection
on the general medical community’s resistance to change, or their lack of
knowledge concerning the benefit of alternative treatments beyond their
specialty? Did you know one in four Cancer Trials fails to enroll enough participants?
And that cancer patients who
participate in Clinical Trials experience better outcomes than patients who do
not.
Clinical Trials occur all the
time, but when was the last time as a cancer patient you heard about a Trial
from your doctor? Many doctors rarely follow-up on postings that come across
their desks for Clinical Trials, they are already swamped and overworked with
patients. Often doctors are little aware of a Trial’s existence, unless the
Trial is directly related to their specialized field. Most likely you will need
to seek out these beneficial Trials on your own, or maybe you will happen to
see a sheet of information about a Clinical Trial posted on a bulletin board in
some obscure location such as the restroom. Public lack of Clinical Trial
information is a travesty, and clearly another contributing factor hampering
the cure for cancer. We could be doing such a better job posting Clinical Trial
information, and doctors could easily provide more information and support for
their clients. Then again, with all the research and results from China and
Japan on PSK and PSP, why are we still trying reconfirm a wheel is round? What
greater volume of tests do we need to accept a treatment protocols with decades
of stellar results, already proven and working extending human life elsewhere
on our planet?
All this brings into question our medical approval system,
and how desperately we deserve a new medical approval process, or at the very
least a truly non-biased funded non-profit research group dedicated to
thoroughly exploring all the non-patentable/orphan, minimal cost, cancer cure
options available from here and around the world.
Should this article inspire you to look for PSK or PSP on
your own, be careful, as what you see on a general internet search may not
provide the results you seek. Many mushroom products available online,
including some labeled as turkey tail, PSK, or PSP, are merely a form of ground
up dried mushrooms. Regarding these, what you need to know is, mushrooms
naturally grow with a cell wall made of chitin. This is an exoskeleton, much like
a crab or lobster, to support the thin walls of the mushroom. This chitin is
indigestible, so eating mushrooms not properly processed will only provide
fiber and basic nutrients with little of the desired medical benefit. Hot water
and secondary extraction is the only proven method to break down this chitin
releasing the desired polysaccharide structurally intact. Therefore when
seeking PSK or PSP, be sure it is a properly processed bio-available product
using a multi-step process including hot water extraction.
A few places where you will want to start your search are Half Hill Farm in Tennessee, Host Defense in Olympia, Washington, or contact Wonder Herb Products Ltd for their representative
closest to your area. By the way, Wonder Herb Products Ltd is the supplier of
PSP used in the Canberra Studies. Wonder Herb also states they have a higher
verified activity level than some other sources. To date, the
best source of tocotrienol I have discovered is made from the annatto plant
found in South America. For around 150 years the seeds of this plant were used
to make food coloring. Then in the late 1990’s, high amounts of near pure
tocotrienols were discovered from the seeds. It is from this plant that
DeltaGold® Tocotrienol is produced and currently sold through multiple distributors.
Unfortunately there is not a good source of naturally pure gamma-tocotrienol,
as yet. More research needs to be completed with additional sources and better
processing. For now, DeltaGold® appears to be the best combination of gamma-
and delta-tocotrienol available due to its lack of tocopherols. As always, you will want to
talk with your doctor about dosage and supervision during PSP, PSK and
tocotrienol use.
There is still more information to come on Potential New
Natural Cancer Treatments. Keep an eye out for the next article in this series
to arrive soon.
Monday, January 4, 2016
Glucosamine To Treat Prostate Cancer
Recently I received an email from a good friend, and cancer
survivor in Australia, relaying a story about a man who believed his prostate cancer
cured with the use of a Glucosamine and Chondroitin supplement. Seems he discovered
this process when he heard men in retirement homes given glucosamine and chondroitin
to improve their joint mobility for exercise, found their PSA going down. Since
he was experiencing a failed prostatectomy, he was open to alternative options
rather than the next step of radiation. He asked his doctor about it who said,
it couldn’t hurt, so he gave it a try. According to the story he began taking
10 caps per day, though I do not currently know the true dosage or length of time
taken. He said after taking the glucosamine with chondroitin, his tests showed
a much lower PSA than normal, with no need for further treatment. The story
goes on to say other men he has shared this information with, have also
received improved results with a much lower PSA. To date I have not been able
to verify this story first hand, though it opened to question these supplements
in relation to prostate cancer and their potential benefit.
I began to wonder why this appeared to help cancer patients,
and completed some preliminary research on the subject. It appears chondroitin
is NOT recommended for men with PCa based on a limited 2002 study that found
men who had a prostatectomy with high levels of chondroitin experienced a 47%
chance of recurrence, whereas men with low levels of chondroitin only experienced
a 14% chance of recurrence. Many medical institutions are now saying that
chondroitin may cause the spread or recurrence of prostate cancer, though research
is minimal, and there is no definitive research for the specific substance
‘chondroitin sulfate’. So until more information and testing are done on
chondroitin, why take the risk?
On the other hand, I found very promising results for Glucosamine in relation to prostate cancer. Research has
confirmed that dose dependent glucosamine inhibits the growth and spread of certain forms of prostate cancer, and causes cancer’s death. There have been
some excellent studies on how glucosamine fights cancer and the mechanisms it employs.
I also discovered glucosamine to be very good at reducing the level of C-Reactive Protein (CRP).
Considering how increased CRP is believed to facilitate cancer’s occurrence and
growth, this in itself could be worthwhile. In addition, glucosamine is a well-known
antioxidant, so it can be paired with tocotrienols that also fight cancer and
reduce CRP such as delta and gamma-tocotrienols in the form of DeltaGold®,
and EGCG therapy in such forms as CAPSOL-T®.
Supplementing with Glucosamine is considered safe, though in
limited instances, mild side effects of nausea, heartburn, diarrhea or
constipation have occurred pending on the dose. Most glucosamine is made from
shellfish though there is a vegan form available. If you have an allergy to
shellfish, you will want to seek medical advise before taking. If you
experience any side effects, it is best to reduce the dose and consult your
medical professional.
To me, the available research brings up some impressive
results for glucosamine in relation to prostate cancer. I now wonder if this is
the principal agent that had been helping retirement patients in the story reduce their PSA, regardless of the potentially negative chondroitin action? Hearing
that several men have had very positive results using a glucosamine/chondroitin
mix is wonderful news; though I believe glucosamine alone may be more effective,
and without future risk of recurrence. For someone concerned with prostate
cancer glucosamine may be an excellent supplement, though it is unfortunate
that glucosamine and chondroitin are so often linked together. At present it is
possible to obtain glucosamine by itself from several sources, or with the
addition of MSM.
MSM (methylsulfonylmethane) is a naturally occurring sulfur
compound. It is present and necessary for health in all people. It has been
principally used for joint health and to reduce inflammation, though it does so
much more. It promotes healthy circulation, cleanses the digestive tract,
improves liver function, boosts metabolism, helps produce glutathione, and
reduces toxic impurities in the body. It also improves cell wall permeability
allowing for greater oxygen to enter, a process believed detrimental to cancer
cells. Sulfur is so important to our bodies that daily we eat many foods containing
sulfur including: meat, fish, fruits, vegetables and grains. Unfortunately
processed, overcooked and dried foods have their sulfur content greatly reduced,
making sulfur supplementation sometimes necessary. Suggested supplement amounts
range from 1,000mg to 4,000mg daily. Supplementing with MSM is considered very
safe but if one’s stool becomes too loose, a reduction of dosage is suggested.
With this said Glucosamine with MSM certainly appear to be an
interesting possibility for future research to mitigate prostate cancer and
lower CRP. As always should you look into these supplements I recommend you
have a discussion with your doctor or naturopath concerning their use, the
dosage, and overall time employed.
Thursday, December 31, 2015
Potential New Natural Cancer Treatments: Is Marijuana a Cure for Cancer?
Cannabis (Marijuana) kills Cancer. Researchers, even the
U.S. government, have acknowledged this as fact. Unfortunately, due to previous
controlled substance restrictions, necessary testing hasn’t been done to
confirm its full curative power, principal healing components, or most
effective dosage. For much of that, we unfortunately rely on unverified
anecdotal stories and limited laboratory studies. Even with a Federal Report
clearly linking cannabinoids found in cannabis to cancer cell death,
retardation of cell growth, and reduction of metastasis that reduce the growth
and spread of cancer, we are still in the dark. By the way, this report also
suggests when cannabis is used with various forms of chemotherapy; it increases
the cancer drug’s uptake, heightening the effectiveness of chemotherapy cancer
treatment.
Once you have tested product, active THC and CBD, treatment
begins. No precise scientific proven dosage recommendations exist. Rick Simpson
suggests working your dosage of Rick Simpson Oil gradually up over time to
ultimately reach one (1) gram per day for a total of 60 days. Biochemist Dennis Hill having declared he cured his Stage 4 Prostate Cancer using
Rick Simpson Oil, suggests simply taking as much as possible in the evening
before bed, then smaller amounts during the day. After 6-months of treatment,
Mr. Hill’s biopsy confirmed his cancer was gone. Now to assure it doesn’t
return he states he takes a maintenance dose at much lower potency with
balanced activated THC and CBD.
Cannabis is certainly complex. There are over 85 unique
cannabinoids found in cannabis. When cannabis is ingested these cannabinoids
travel through the blood to eventually lock onto many different cannabinoid
protein receptors on the surface of cells. Some of these receptors are
classified as CB1, CB2, and a family of receptors known as GPR. CB1 receptors
are more abundant throughout the nervous system. CB2 receptors are mostly in
the immune system. CB1 and CB2 receptors are also found on cancer cells
assisting with regulation of cell death and growth. And a combined receptor
composed of linked CB2R with GPR55 is even more abundant on cancer cells. Because of the nature of cancer, when cannabinoids
lock onto cancer cells the reaction is considerably different than when they
lock onto healthy cell receptors. Cancer cells have far more receptors than
healthy cells and have a different reaction to the THC and CBD than healthy
cells. Essentially the cannabis while killing cancer cells leave healthy cells
unaffected. For our purpose here we are focusing
principally on two cannabinoids, THC and CBD. This in no way implies other
cannabinoids do not play a part in the healing process. It’s just not yet
understood, needing further research.
THC is the substance that gets you high when you smoke,
drink, or eat cannabis, marijuana, or ‘pot’. If you grew up in the 60’s you may
understand this process all too well. THC is also one of the principal ingredients in cannabis that kills cancer. When activated, it easily attaches
to cancer cells via cannabinoid receptors. This process generates a ceramide, a
lipid molecule, disrupting the mitochondria, shutting down the cell’s energy flow. As a result, the mitochondria release ctochrome-c, a protein that catalyzes reactions, and ROS (reactive
oxygen species) into the cytosol, the fluid found in each cell.
Additionally the calcium chemical process in the mitochondria is further
damaged. These actions cause the cancer cell to die. So largely THC works on an
oxidative process within cancer cells. For this reason it is important to
reduce the amount of antioxidants ingested during cannabis treatment, and be especially careful of any large amount of antioxidant
food or supplements within 6-hours before or 4-hours after a cannabis
application.
CBD on the other hand operates differently. When it locks
onto the cancer cell it disrupts the endoplasmic reticulum that facilitates
transportation of proteins within the cancer cell by destroying the calcium
functional process of the cell. This causes calcium to flow into the cytosol
causing cell death. In addition, it facilitates the break down of proteins and
peptides in cancer cells, again causing their death.
Together THC and CBD found in cannabis deal cancer a one-two
punch. Limited research has shown THC effective at killing cancer cells and CBD
not only assisting with the death of cancer cells but especially effective at
stopping metastasis. In the lab, cannabinoids have been found to stop cancer
cells from dividing, to prevent new blood vessel growth supplying tumors, and accelerating cancer’s own waste disposal process,
called autophage, which also assists in cancer cell death. Bay area
researchers McAllister and Desprez recently confirmed cannabis inhibits
cancer’s progress keeping it from metastasizing. In addition when used together, CBD assists to mildly reduce the ‘getting high’ effects of THC making the entire treatment process a bit easier.
Without doubt, cannabis contains many interesting and
healing properties. In addition to arresting cancer, it has been linked with
reduced inflammation and seizures, moderating stomach issues, reducing anxiety,
depression and psychosis, and helping to resolve neurodegenerative disorders.
With all of these benefits many have jumped on the bandwagon offering Internet
promotions for CBD oil; yet cannabis is still illegal throughout much of the
U.S., so what are they really promoting? Unfortunately, what they’re offering
on the Internet will be of little use to cancer patients. You see there are two
forms of CBD oil, one made from cannabis, the other made from legal commercial
hemp. Though in essence the same plant family, they are far different products.
So be very careful in what you buy. Commercial hemp oil, also sometimes sold as
CBD oil, actually contains very little beneficial CBD, only 25 parts per
million; whereas cannabis CBD oil has naturally occurring CBD at around 150,000
parts per million. You will not receive the benefits you need from commercial
hemp oil. Also products sold on the street labeled CBD oil or Rick Simpson Oil
may include unknown ingredients, may have reduced potency, or have been
manufactured in such a way to compromise the healing properties of the
cannabis. For prostate cancer you need the highest quality of purified
activated THC and CBD, preferably in a one to one ratio. So where can you find
these products in the safest possible manner?
You could start by obtaining a legal medical card if you
reside in any one of the 23 U.S. States and Washington, DC now approving medical marijuana use.
And the list just keeps growing. This has the benefits of providing cannabis in
the most standardized form and quality, with the lowest possible price. Most
states only require residency along with a valid medical examination or
consultation, and proof you have a condition that will benefit from cannabis
treatment. Cancer usually tops their list. When going to this appointment, be
sure to bring your cancer documentation such as lab tests, scans, and biopsy
reports. After the exam, you’ll be issued a medical marijuana card or
certificate to take to a licensed dispensary of your choice. There you will be
able to purchase product for treatment. Of course if you’re fortunate to live
in Colorado or Washington State where recreational marijuana is now legal, you
have the benefit of being able to go to the store for purchase, though the
specific product you want may not be carried in their inventory. You’ll also
find this retail process more expensive and technically you’ll still need to be
a state resident. You know, if it came down to it and you really wanted to try
cannabis for your cancer, I would not hesitate to move to a state where medical
or recreational forms are legal. It keeps you safe, and legal, for the 3-4
months of self-treatment, and it’s a lot less costly with fewer side effects
than many accepted cancer treatments.
When purchasing product you want to look for THC and CBD oil
combined in roughly a One to One Ratio. Most often attaining this ratio will
require combining two or three products. Many of these products, looking like
black or amber goo, come in tubes, or small syringes without the needle.
They’re sold as CBD Oil, Rick Simpson Oil (RSO), or possibly a CO2 extracted
oil. When first looking for acceptable product, you’ll find that the ratios of
THC to CBD vary greatly from location to location, and product to product. Pay
particular attention to ‘fully tested and certified’ product. Before purchasing
any product, you need to know the following:
1) What are the percentages of THC and CBD per gram of
product?
2) What are the percentages of Activated THC and Activated CBD?
2) Are there any solvent residues present?
4) Are there any traces of foreign material and microbial
contaminants present?
Presently a typical product selection may include tested
results such as these:
Product A) High CBD oil:
15.34% Total THC, 59.98% Total CBD, with Total Activated
Cannabinoids 61.93%
Product B) High THC RSO oil:
81.26% Total THC, 0.24% Total CBD, with Total Activated
Cannabinoids 85.40%
Let’s take a look at how these numbers affect your THC and
CBD mixing ratio.
In 1 gram of our example High CBD oil there is:
1,000mg
X 15.34% = 153.40mg THC
1,000mg
X 59.98% = 599.80mg CBD
This
equals a THC/CBD ratio of 1 to 3.91 roughly 1:4
Total
Activated Cannabinoids in Product-A are listed as = 61.93% of total volume and
are in a roughly 1 to 4 ratio. These include all cannabinoids in the product,
not just THC and CBD though these are the principal components. Now remember,
we are looking for a close 1 to 1 ratio of activated THC and CBD. Thus we need
to add some High THC oil into the mix.
Next, in one gram of the example High THC oil there is:
1,000mg
X 81.26% = 812.6mg THC
1,000mg
X 0.24% = 2.4mg CBD
This
equals a THC/CBD ratio of approximately 339 to 1
Total
Activated Cannabinoids in Product B are listed as = 85.40%
Given the THC and CBD numbers in One Gram of Product-A,
for a 1-gram daily dose using these products, I might suggest combining
approximately 2/3 gram of Product-A and 1/3 gram of Product-B.
This process becomes further complicated when the activated
Cannabinoids total much less than total THC and CBD, as activated
cannabinoids are required for effective
treatment. You can see why
having reliable test results and proper labeling of cannabis products is so
important. Without product test results, you are only guessing. Can you treat
without knowing the numbers, possibly… but most likely not in a successful manner.
At this time researchers and doctors tend to agree that keeping your activated
THC and activated CBD ratios balanced will provide the best possible results.
It may take you some time to find the best product(s). Just keep asking
questions, and if one outlet is unable provide you
with a verifiable breakdown of their product’s components, go somewhere else!
As a last resort you could make your own product by
purchasing unprocessed marijuana and cooking it. There are several strains of
marijuana that have been breed for different purposes. Some strains have almost
breed out all the CBD in favor of higher THC. For treatment, you will be
looking for an Indica Strain, not Sativa, with balanced CBD and THC. Using this
product you might try making your own hash-oil, which is a very dangerous
process when done improperly. This process is not only toxic, but has caused fires
and explosions when performed in a confined space. Besides it stinks, and the
neighbors will quickly come to the realization what you’re doing. The person
who pioneered this process, and popularized treatment of cancer with cannabis,
is Rick Simpson. His story and his hash-oil process may be found on the web at PhoenixTears. But because
of the dangers of this extraction process, I do not recommend it.
Recently, a less volatile home
based process has been added to create product for treatment. Again you start
with the raw marijuana but then you process it with coconut oil over low heat
(180 degrees F) for around 11+ hours. This forms a cannabis paste. Since no
volatile solvents are involved, the entire process is much safer. Of course,
with this process you will still need to pay for your own finished product
testing that in itself will be costly in small batches, both in terms of
dollars and consuming available product. Full testing can run over $200, and
consume from 2-4 grams of finished product. Not an expense an individual user
wants to undertake.
Because of this, my preference
would be to legally buy your finished, fully tested, product from a reliable
source. But if that’s just not possible, here is one cannabis paste process:
Start with at least 4-8 grams of
Buds that have been properly tested so you know the ratio of CBD to THC. Spread
these on a cookie sheet and dry them in the oven at low temperature (180º F)
for 1-2 hours. When sufficiently dried, remove and blend the cooled Bud into a
fine powder mixture in an electric coffee grinder, or similar product. Then in
a double boiler on the stovetop, like you would use for melting chocolate,
cover the powder with roughly an equal volume of melted coconut oil. Heat slowly
on a ‘low’ temperature of 180º F to 200º F for at least 11 hours. Check
temperature of this mixture with a thermometer often during the process. After
cooling have resultant paste tested for mixture ratio and percent of activated
product. If you think this sounds like a lengthy process, you’re right. It’s
also a mess to clean up, and it stinks. So once again, it’s best to seek out
legal pre-made product that’s been properly tested. More about this cannabis
paste process is available online.
Why does one desire heated marijuana for treatment? It’s to
convert it into an effective product for the body to use. Raw unprocessed
cannabis contains mostly THCA; this simply doesn’t fit effectively into the CB1
receptor. The same applies to CBD. When properly heated during the process to convert
CBD and THC, the heat causes a carboxyl group to be removed thus creating
active THC and active CBD. The process is called decarboxylation. It’s best done at low temperatures over time preventing
destruction of cannabinoids and terpenes in the cannabis. This new Activated
THC and CBD will now fit perfectly into the CB1 receptors on cancer cells.
Regardless if you are using RSO Oil, Cannabis Paste, CO2 Extracted Oil or CBD Oil,
the extraction process requires heat over time to decarboxylate and activate
the finished product. The problem becomes at what temperature. Too high a heat
will destroy the beneficial properties of the cannabis, while too little will
not decarboxylate the THCA and CBDA. Biochemist Dennis Hill, who states he
successfully treated his Stage 4 prostate cancer with cannabis, suggests the
optimal heat is 240 degrees F for 30 to 45 minutes. Heat may also be applied at
lower temperatures for a longer time creating the same results, such as in the
long processing time of cannabis paste.
If you have decided this may be a path to try, above all
else remember, THC will make you high, possibly impairing reflexes and
judgment. Do not plan on normal activity levels during the course of treatment,
and never, ever, put those around you at risk when ‘buzzed’ on THC. Remember this
is an experimental cancer treatment, be responsible!
Little has been written about the debilitating effects of
short term high-dose cannabis treatments. When taken orally in high doses, you
may find yourself unable to function at the most basic tasks. Even a trip to
the bathroom can be challenging and difficult to navigate. This is because
around half of the ‘oral’ THC is converted in the liver into a strong psychoactive
metabolite called 11-Hydroxy-Δ9-tetrahydrocannabinol that gets you incredibly
‘high’. Immediate side effects of treating orally with THC include sensory
distortion, poor coordination, slower reaction time, lowered blood pressure
that may cause fainting, and possible panic or anxiety. There is also the
possibility your heart may speed up during the process so be sure to have it
checked prior to treatment, and find a doctor who understands cannabis follow
your progress. After the initial high, many feel sleepy or even depressed.
Suggested long-term side effects could include suppression of the immune
system, sexual difficulties, mood changes, and the inability to properly
reason. These long-term side effects have been witnessed after years of cannabis
self-indulgence, therefore the few months of cancer treatment will most likely
not be an issue. Still everyone is biologically different, so beware. Needless
to say the side effects most often experienced are far less than those from
many standard medical treatments for cancer.
One last note regarding possible side effects and withdrawal
symptoms, when taking 1 gram of cannabis per day your body will become attuned
to the cannabis. If you quickly stop the treatment, withdrawal symptoms will
occur. These could include night sweats, interrupted sleep, vivid dreams, and
general flu-like symptoms. Symptoms usually last for 3-5 days, gradually
tapering off. To avoid withdrawal, the best process is to lower your cannabis
dosage very slowly over several weeks time, and be sure to contact your doctor
if symptoms persist.
You may also want to discuss with your doctor using
Citicoline during cannabis treatment and/or at withdrawal. This is a readily
available supplement in the U.S. with a reasonable safety track record. Most
common side effects for large doses include stomach upset and diarrhea. Some
believe it can be used during treatment to mitigate the side effects of THC
psychoactivity reducing such side effects as paranoia and anxiety, while
improving focus and mental energy. This is believed to allow for a quicker
dosage ramp-up and easier withdrawal. The suggested use during treatment is to
take 250-500mg one hour before a cannabis dose. More research on this product
and dosage needs to be done. Citicoline facilitates production of
phosphatidylcholine a chemical important for brain function. It may also
protect against brain tissue damage, improve visual function, increase brain
glucose metabolism, increase dopamine receptors, and prevent memory impairment.
Again, few studies have been completed regarding this product and cannabis
though it has been used for many years. A June 2014 review of literature regarding Citicoline concludes that it is considered neuroprotective against
the neurotoxic effects of drug use thereby reducing withdrawal symptoms.
Having said all this, there may be a way to avoid the
extreme debilitating highs when using cannabis while possibly improving cannabis
absorption. Though more testing is needed, the solution appears to be through rectal
administration using available, or
homemade suppositories, or 1CC slip or soft tip syringes (without needle) with
RSO or CO2 extracted oils. Using this method, the THC and CBD avoid
the digestive track and liver, and travel
into the body through the vena cava allowing for much better bioavailability,
higher blood concentrations that begin sooner and last longer, and fewer psychoactive
side effects. Suppository molds, and 1CC slip tip syringes are easily available
through Amazon.com. Those who make their own suppositories often use cocoa
butter as a carrier as it is solid at room temperature, melts in the body, and
is generally soothing and non-irritating. If you are fortunate enough
to live in Colorado, there already exist legal outlets where properly tested
cannabis suppositories are available, along with medical doctors who will
provide advise regarding their use.
In addition to the potential healing properties of THC and
CBD, positive side effects of using suppositories in this manner include reduction
of hemorrhoids and rectal inflammation, and you are able to function much
better on a day-to-day basis during treatment.
Making cannabis suppositories at home is relatively easy,
especially with single-use suppository molds available online. Start with a
ratio of 10 grams of cocoa butter to 1-2 grams of activated cannabis oil. After
doing your calculations regarding percent of activated THC and CBD for each
product, you will know what amounts of THC and CBD to combine to achieve the
nearest 50/50 ratio of THC and CBD. Cocoa butter is also available online, or
from any good chocolate store.
Now use very low heat to slowly melt the cocoa butter. Be
careful not to burn the oil. Using a double boiler often used to melt chocolate
is recommended. Then add the cannabis oil and stir thoroughly until evenly
distributed and mixed. This may take some time. Once mixed, pour the warm fluid
into the suppository molds, and set aside to harden. You can facilitate this
process by placing the filled molds in the refrigerator or freezer. These
low-dose suppositories are now ready for use. As you continue to use the
cannabis, gradually increase the amount of activated THC and CBD in the
suppositories over time. Your goal is to reach a point where your have 1 gram
of a 50/50 THC and CBD blend in each suppository with at least 70-80% activated
product. Once this is reached, continue with application for two months and
then test your cancer markers. During this treatment time, pay particular
attention to staying hydrated. Drink extra water and electrolytes to prevent
rectal dehydration that tends to reduce rectal absorption.
Throughout this section, I have repeatedly written about
using properly tested legal product. With each State creating individual
diverse laws for the legalization of medical marijuana, there is much to be
desired concerning the quality of available product. In some instances, even
with purchasing product from a legal source, you may not receive what’s
advertised, or even have available the product you need.
For example, buying product in Washington State at this
writing is a bit like buying products in the Old West out of a covered wagon
that just pulled into town. Medical marijuana outlets range the gamut from
sleazy dives to clean well-run medical facilities. Within each of these
facilities, the greater abundance of product is without test results, and staff
often has minimal product knowledge. Then when the marijuana does include some
published ingredient information on the packaging, the information may not be
complete or there is little backup documentation. That’s right, the product may
be labeled for THC, and or CBD percentage, but does not come with the test
report verifying the printed information, percent of ‘activated’ product, or if
there are residual solvents or biological contaminates. Instead the purchaser
often hears, “trust me, others are getting good results”. Even finding product
can be a problem. Most dispensaries of medical marijuana have little high quality
CBD available. You see much of the available plants are now genetically grown
to enhance THC, not CBD. For cancer patients, this is a continuous issue.
Then there is the secret shopper Report from New Mexico. A neuropathy patient, working with
a local newspaper and testing lab, purchased 14 cannabis products from shops in
the Santa Fee and Albuquerque areas. What they discovered was disappointing.
While some products tested as advertised for quantities of THC and CBD, many
only contained 10% to 50% of labeled quantities. This is a clear case where
patients in need were being sold substandard product.
What can be done about these deficiencies and abuse? Until
we have Federal approval and uniform product regulation, patients should refuse
to purchase any product without full test reports openly available. Further, I
believe States that provide approval for medical marijuana need to setup their
own ‘secret shopper’ random testing program with large fines for any licensed
retailer selling substandard, untested product to medical marijuana patients.
Fines and licensing fees could easily cover the cost of shoppers, product purchase,
and testing. Clearly the system to date is not perfect, though I believe we are
headed in the right direction, and medical marijuana does appear to be getting
results.
Does cannabis work to cure cancer or put it into remission?
You be the judge. Cancer cure rates are largely unknown; to our disgrace as yet
no major patient studies have been completed, though excellent results have
been obtained in smaller clinical trials and laboratory settings. All you can
do now is read as many smaller studies and personal stories as possible, both
the good and the bad, then make your own decision. The good news is the choice
is yours.
Laboratory studies have been promising. So much so that one
recent 2013 study clearly supports full clinical testing of CBD for treating
prostate cancer.
From around the world there are many medical studies that support the use of cannabis to treat cancer in many of its forms including
brain cancer, breast cancer, lung cancer, prostate cancer, blood cancer, oral
cancer, and pancreatic cancer. A 2006 study with patients suffering from glioblastoma multiforme who previously experienced failed treatment with
surgery and radiation found life extension with THC usage. A 2010 breast cancer study confirmed that THC reduced tumor growth and the
severity of lung cancer metastases. A 2008 study by Harvard Medical Schoolfound that THC inhibited lung cancer cell migration, and recommended that it be
explored to control growth and metastasis of various cancers. A Swedish 2006 study confirmed that cannabinoids kill mantle cell lymphoma.
Another study relating to oral tumors showed cannabinoids are toxic to malignant tumors.
In addition there are many stories from patients who reported melanoma cures
through the use of topical cannabis oil. Foundation for this process is backed through
limited recent such as the 2013 paper, ‘Epigenetic control of skin differentiation genes by phytocannabinoids’,
and the 2015 research study ‘Differential role of cannabinoids in the pathogenesis of skin cancer’.
And the list of healing stories and research goes on. For
further information you may also want to visit the Alchimia Blog to view a list of 82 studies of
marijuana in relation to cancer. Clearly cannabis is providing some form of
positive healing results for treating cancer. Why then if we truly want to cure
cancer, do we not do everything within our power to explore it further? Could
it be the stigma of getting high or that it is not socially and politically correct? More likely it is because there is no major financial
return for pharmaceutical companies? Cannabis is easy to grow, much less
expensive compared to new approved drugs, and available around the world.
Because of this the question becomes, “Regardless of its ability to relieve
suffering and save lives, who will fund the millions needed to do the research
for its official approval?”
Stay tuned for my next post in this series on Potential New
Natural Cancer Treatments.
Wednesday, November 18, 2015
Potential New Natural Cancer Treatments - Artesunate
Artesunate, Artemisinin & Artemether
Are you looking for a
cancer treatment that attacks, and kills cancer cells with little harm to
healthy cells? Now add, it should have zero to minimal side effects when
administered properly, cost less
than $3.00 per day for treatment, and obtain excellent results. The answer may
be closer than you think.
One of the most promising
new cancer treatment possibilities is Artesunate, a standardized pharmaceutical grade derivative of
Artemisinin from the Artemisia annua plant, also known as Sweet Wormwood or
Sweet Annie. Artemisia annua has been used in traditional Chinese medicine for
thousands of years. In fact, records of its use were unearthed in an ancient
Han Tomb at Mawangdui outlining treatment for malaria with Artemisia. Also
discovered, was a small region in Viet Nam that has been quietly relying on the
Artemisia Anna plant for its malaria healing powers.
As a result of these
discoveries, in the 1960’s the Chinese began using this plant to treat malaria.
In the 1970’s the World Health Organization began investigating Artemisia annua
as a malaria cure when Quinine became less effective. And in 1972, Artemisinin
was isolated from the plant by Dr. Tu Youyou of China as one of its principal
active ingredients. For this discovery and his work with Artemisinin, Dr Tu
received a Nobel Prize in 2015.
Since then,
Artemisinin, and its two most common derivatives, Artesunate and Artemether,
have been used around the world to treat malaria. Artemisinin works because malaria parasites
consume large quantities of red blood cells containing iron. They become loaded
with iron. Adding Artemisinin causes a reaction with this iron releasing
reactive oxygen species that destroy the parasite.
In the U.S., the FDA has
also approved a drug made from this research for malaria treatment. In
addition, because of Artemisinin’s extended use, there are excellent records
for dosage, effectiveness, and side effects regarding the Artemisia annua
plant, Artemisinin, Artesunate, and Artemether. So what does this have to do with cancer? The
answer revolves around malaria and cancer’s need for iron to survive.
Now fast forward to
present time. Due to recent research, some provided by the University of Washington, scientists are looking at the Artemesia family of
compounds as a treatment for cancer. In fact, preliminary research has progressed
so well that one company in the Pacific Northwest, working to improve
Artemisinin’s effectiveness, is ready to initiate phase one trials in relation
to breast and prostate cancer, as soon as they are able to fund the project. So you’re probably asking yourself, how does it
work? To answer, it’s important first to understand one of the principal
processes of cancer cells. This is, cancer’s critical need for iron.
Iron is essential for each
cancer cell’s metabolism, cell division, and survival. It plays a part in DNA
synthesis, cellular respiration, and macromolecule biosynthesis. It is vital
for cell growth and proliferation. In fact, it is so necessary for cancer cells
that without it they die. Now we all need a certain level of iron for proper
bodily functions. Too little iron, you become sick and anemic. Too much iron and you could experience chronic
fatigue, joint and abdominal pain, even liver and heart failure. And an over-abundance of iron is also believed to
fuel cancer’s growth like pouring gasoline on a fire.
Normal cells in your body
need minimal iron, but cancer cells need more. It’s their key for cellular
division. To gather the iron cancer needs, prostate and breast cancer cells
have many more transferrin iron-receptors on their surface than healthy cells,
as many as 15 times more! Leukemia cancer cells require the highest
concentration of iron. Their iron storage can reach 1,000 times more than
healthy cells. All this iron comes from the food we eat.
When we consume foods with
iron, the iron is absorbed by the small intestine. It’s then carried to the
cells by a plasma protein called transferrin. Our cells have transferrin
receptors on their surface. Sort of like a receptacle or dock waiting for its
mate or ship to arrive. As the
iron carrying transferrin joins with each cell’s transferrin receptors, it’s
transported into the cell by a kind of vesicle, essentially a sac. The
transferrin is then released into the cell and the empty receptor is
transported back to the cell surface to gather more transferrin. This is a
process of continuous repetition, though much more abundant for cancer cells
due to their greater quantity of transferrin receptors. In addition to cells
collecting iron, much iron is transported to the bone marrow where it’s used to
make hemoglobin and red blood cells. These then circulate throughout the body
supplying oxygen to tissues and organs. Iron in the blood is an important
factor when considering Artemisinin treatment, and it also presents an
excellent way of monitoring for side effects. More on this later.
Now comes the important
cancer termination part. The
Artemisinin family of compounds contains two oxygen atoms hooked together in an
endoperoxide linkage. When put together with iron this bond breaks, thus
forming free radicals that destroy the cancer cell from within.
Technically Artesunate,
which is readily hydrolyzed back to a DHA metabolite, is activated by iron in
the cancer cells. This combination produces highly alkylating carbon-centered
radicals and reactive oxygen species (ROS). Because tumor cells are already
damaged, they have lower expression of antioxidant compounds and other factors
necessary to repair the damage caused by the flood of alkylating
carbon-centered radicals and ROS. Thus the cancer cell ceases to function.
Healthy cells require much
less iron. They also are better equipped to repair oxidative damage. Because of
this, Artemisinin effectively targets cancer cells while leaving healthy cells
in tact.
Though few official
studies have been completed, reported results from cancer patients taking
Artemisinin Compounds are remarkable.
• A 47-year-old male with
an egg-sized head lymphoma who took Artemisinin for two
weeks experienced complete healing four weeks later. The tumor was gone with
no mass remaining.
Then, there is the recent Colorectal Cancer Study from St George’s University of London combining Artesunate followed by curative resection. This was a 14-day, randomized, double blind, placebo-controlled pilot study. Follow-up revealed, of the 11 patients on placebo, six experienced a cancer recurrence within 3.5 years, three of these died. Whereas, only one of the nine patients on Artesunate experienced a recurrence, and none died. Given the very short time on Artesunate, these are fascinating results.
• A woman with stage-4
breast cancer after receiving Artemisinin derivatives reported renewed
wellness, feeling like before she was diagnosed with cancer. Her CT Scan
confirmed remission.
• A 40-year-old woman with breast cancer and spine metastases after four months
of supplementation with oral Artemisinin derivatives showed no remaining cancer
on her spine using a PET scan.
• A woman with metastasized
breast cancer was able to stop her drug use of zoledronic acid and Tamoxifen
with her oncologist’s understanding because her cancer markers had so improved
after taking a course of Artesunate.
• A male, with larynx
cancer treated with Artesunate injections for two months was able to shrink his tumor by 70 %.
• A Belgium man with a PSA
of 12 reported his PSA dropped to 0.38 with Artemisinin derivative treatment.
• Others with prostate
cancer have been able to drop their PSA significantly with Artemisinin and
derivative treatment, from 4 to 2, from 7.8 to 1.9, and from 3 to 0.45
respectively, all within 3 to 6 weeks.
Then, there is the recent Colorectal Cancer Study from St George’s University of London combining Artesunate followed by curative resection. This was a 14-day, randomized, double blind, placebo-controlled pilot study. Follow-up revealed, of the 11 patients on placebo, six experienced a cancer recurrence within 3.5 years, three of these died. Whereas, only one of the nine patients on Artesunate experienced a recurrence, and none died. Given the very short time on Artesunate, these are fascinating results.
In all, at least 55 cancer cell lines appear to experience some level of cancer cell death and remission
with Artemisinin derivatives… with leukemia, colon, melanoma, breast, renal,
CNS, and prostate cancer
showing the best results.
Additional research papers
on the Artemisinin and its derivatives may be found through the University of Washington.
This is exciting
information. But do NOT rush out to your local health food store, or onto
Amazon.com to purchase
Artemisinin. It may not work. Testing on readily available Artemisinin products
has revealed capsules containing wide ranges of potency, some with only 5% to
10% active Artemisinin levels. Using these products is most likely a waste of
time, money, and your health. There is too little Artemisinin to be effective.
This is due to processing, and that different subspecies of Artemesia annua
contain different concentrations of Artemisinin. The species with the best
yield and quality is found in southwestern China and Vietnam.
Then too, Artemisinin and
its derivatives are light sensitive, loosing potency when exposed to light so
packaging and storage are very important. And since successful treatment, and
side effects are dose-dependent, it is critical to know exactly the amount you’re
taking. Therefore, the only Artemisinin family product to consume must be of
‘pharmaceutical grade’ quality.
There are several pharmaceutical grade sources for Artemisinin family products,
but which form of Artemisinin should be used?
Several derivatives of
Artemisinin have been developed since it’s recent discovery in an attempt to
improve absorption and stability while reducing toxic effects. Currently,
doctors principally use three product forms. Let’s start by looking at each of
these.
Artemisinin – This is the initial product derived directly
from the Artemesia annua plant. It is Not Water-Soluble and has poorer
absorption than some other forms. When taken, it reaches its peak concentration
in the blood in about 40 minutes. The liver quickly breaks it down, and by four
hours it has reached the end of its effectiveness.
Artesunate – This is a semi-synthetic form of Artemisinin. Many
sources believe it is the most effective form to use for killing cancer because
of its DHA conversion in the body.
Artesunate is partially water-soluble. It is available in pill, injection, and
IV forms. It has a higher absorption rate, around 61%, but also the shortest
activity period.
Artemether – Another semi-synthetic form of Artemisinin,
Artemether lasts longest in the blood and is more fat-soluble. It also exhibits
more side effects than the other two products.
Important
Note: Because of its higher
toxicity, it has been strongly recommended that Artemether dosage not exceed
one milligram (mg) per kilogram (kg) of body weight per day (<1mg/kg/day).
Now knowing the different
forms of Artemisinin, have a conversation with your health care provider to
choose which approach may be best. From my own research and medical
discussions, I tend to believe Artesunate to be most effective, though in some instances a blend of the three could be explored.
For all three of these
forms, most doctors and researchers recommend they be taken on an empty
stomach, away from food. If taken near food consumption, the Artemisinin may
bind with iron in the food rendering it ineffective before reaching its cancer
target. If taking these products
twice a day the best times are just before bed at least three hours after
eating, or in the morning an hour before food.
But if you are taking
supplements, Vitamin-C, CoQ10, Fish Oil, etc., taking Artesunate or Artemisinin
twice a day may be not practical. You see many supplements are strong antioxidants.
The Artemisinin family works largely on the principal of oxidation. An
antioxidant will counteract this oxidative process. Your supplements most
likely stay in your body at least four to six hours. If taken too close to
Artemisinin, your supplements will negate its use. Then too, one must consider
your nutritional intake. You wouldn’t want to eat say a couple of oranges close
to ingesting Artesunate because of the anti-oxidants. And, there are many foods
with higher anti-oxidant activity. Some of these include red beans,
blueberries, kidney beans, pinto beans, cranberries, artichoke, blackberries,
prunes, raspberries, strawberries, apples, pecans, cherries, plumbs, potatoes,
black beans, and the list goes on. Then there are all the exotic super food
antioxidants. So what’s a person to do? You shouldn’t stop eating healthy. The
answer is to simply separate the two. Enjoy your high antioxidant foods and
supplements in the morning, and take Artesunate in one dose at night before
bed.
With that said, there is
another reason to take Artesunate before bed. Cancer cells grow faster at
night. This is when protein receptor molecules on the cell’s surface are more
active. The epidermal growth factor receptor (EGFR) facilitates cell growth,
but is suppressed by another receptor during the day. All this cancer growth
activity at night makes the cells more vulnerable, requiring more iron for
cellular division. Bedtime then becomes the best time to slip in a little Artesunate,
Artemisinin or Artemether.
Other points to consider
are absorption, and absorption resistance. The Artemisinin family is mostly oil-soluble, not water-soluble.
Artesunate’s increased absorption rate comes from its partial water solubility.
For best absorption, some doctors are researchers suggest taking the dose with
a little whole milk as it has fat to facilitate absorption with few
antioxidants.
Then, when you ingest
Artemisinin continuously your intestines quickly build up a resistance to
absorbing the Artemisinin. In only a few days, amounts of Artemisinin absorbed can drop by over 30%. With continued use, this drop in absorption
increases until the Artemisinin attained is far too little to be effective. The
easy remedy for this issue is an intestinal reset. When one stops taking Artemisinin
for a few days, absorption is believed to return to its necessary levels.
Before we continue with
this discussion, I want to add an important warning. There can be serious side
effects as a result of taking Artesunate, Artemisinin or Artemether in too large
a dose without concurrent monitoring of hemoglobin and other appropriate tests.
If you are considering using Artemisinin in any of its forms, it is vital you
use it only under the supervision of a medical professional that understands
the process, and can perform the safety and evaluation tests required.
With that said, let’s
continue by focusing on dosage, and side effects. There are a few studies that
provide a hint of dosage for Artesunate and Artemisinin as it relates for
cancer treatment, though many studies exist for malaria. Doctors around the
World have been using Artemisinin in its three principal forms for malaria
treatment for decades. Therefore we do know something about dose tolerance.
Recent research, along
with doctors and researchers I have chatted with regarding this subject, generally
suggest the following Artesunate protocol
for treatment:
•
Prior to use have your iron levels and hemoglobin tested
If low - these need to corrected before proceeding
•
Artesunate Dosage:
2.5mg
to 3.5mg per kilogram of body weight per day
•
Take dose before bed,
away from food and antioxidants,
with
a little milk
• Take
5 days on then 2 days off for best absorption
•
After 14 days test Hemoglobin Levels –
This is critically important!
If no change in Hemoglobin on initial 14-day test–
Talk
with doctor about a small dosage increase
If
Hemoglobin dropping –
Reduce
dosage and retest until stability reached
•
Continue for another 14 days – re-check Hemoglobin
Once Hemoglobin level is stable – re-check every 30
days
•
Check for liver function
•
Check cancer markers for results at 30 days, and as desired.
Research suggests, if the
Artesunate is administered properly, positive results in cancer markers should
be seen after the first 28 days. I know cancer survivors who have taken Artesunate
for months with desired result starting small, then building. Treatment is
without side effects for the most part, though some have experienced issues.
Side Effects are often dose-dependent. When side effects show
up they can present as stomach or digestive distress, though in rare instances
flu-like symptoms of dizziness, fever, nausea, skin rashes, drowsiness,
sweating, even vomiting has occurred. Some people with allergies to ragweed
related plants also experience an allergic reaction. In one study with 500
patients, approximately 50% of the participants taking Artemisinin compounds
experienced some form of minor side effect with no major side effects during
treatment. These side effects though concerning, can be
controlled with your doctor’s help. But woe to those who take Artemisinin
compounds without counsel and medical supervision.
If taken without regard
for proper dosage and monitoring, more serious dose-dependent side effects can
exist. There have been rare instances
of large doses of Artesunate and Artemisinin attacking bone marrow and red
blood cells. Nearly 70% of the iron in your body is stored in red blood cell’s
hemoglobin and muscle cells. Too much Artemisinin, Artesunate, or Artemether
may begin to attack your hemoglobin, or the bone marrow where red blood cells
are made. This can result in anemia or abnormal bone marrow. Too much
Artemisinin may also effect to liver.
These situations are
thought to be easily avoided by monitoring your hemoglobin level at specific times, then
adjusting the dosage of Artesunate, Artemisinin or Artemether as required to a
maintain proper hemoglobin level.
Contraindications
for the use of Artesunate, Artemisinin or Artemether may include allergy,
pregnancy, low weight, anemia, hearing or balance problems, liver disease, or
adverse drug interactions. Though the Artemisinin family has been successfully
tested to enhance 22 cancer drug therapies, in some drugs like doxorubicin, it
makes the drug less effective. Again, be sure to cover drug interactions with
your doctor.
Lastly,
a warning! If you have recently experienced radiation therapy, do not use
Artesunate, Artemisinin or Artemether for up to months. When healthy cells
experience radiation they go into a repair mode. This requires extra iron.
Adding Artemisinin compounds during the repair time could hinder this cellular
repair, disrupting the healing. On the other hand, using Artesunate,
Artemisinin or Artemether before radiation has been show to enhance the cancer killing effect of the radiation.
Now
you know the most recent facts, where do you go from here?
There
are two quality sources for Artesunate, Artemisinin or Artemether providing
tested pharmaceutical grade products. The Artesunate suggested in the one
treatment scenario above is labeled Hepasunate 50 and comes from a company
called Hepalin. Another
quality source of Artemisinin comes from a company named Holley Pharmaceuticals. Both of these companies are located in California.
Is
Artesunate a treatment for your cancer? Limited research, medical opinions, and
stories from cancer survivors indicate it, or a close form, could well be the
treatment to put cancer into remission. One doctor indicated he has only
witnessed improvement in his cancer patients using this process, and many of
his patients have experienced profound healing. Are there some people where it
has no effect? This may also be possible considering there are over 100
different types of prostate cancer with slightly different reactions. Each
person’s cancer and body is unique though this oxidative process appears to
bridge the gaps between many forms of cancer.
People
around the Globe have been taking Artemisinin and its derivatives for years
with success for malaria, and now for cancer. New research is being
accomplished, though unfocused and grindingly slow. Much research still needs
to be done. You see no pharmaceutical wants to fund a cancer drug’s research
without financial return. Artesunate, Artemisinin and Artemether are already
commercially available at around $3.00 a pill, and new derivatives will not be
that much more. So where’s the profit? And without financial research backing
for human trials Artesunate, Artemisinin and Artemether will never see FDA
approval. Does lack of FDA approval mean that it doesn’t work. Not in the
least. It just means that this is one of those promising cures kept from
official approval due to our system and lack of funds
This
is the First of Five Promising Cancer Treatments. Over the weeks to come I will cover each treatment
with the most updated information available. In each case these potential
healing processes, due to lack of future financial return, have been excluded
from proper research and trials thus eliminating them from FDA approval. At the
end of these articles, I will propose several solutions to this problem and
hopefully a process to increase cancer remissions and enhance the quality of
our lives.
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